Article
The zebrafish retinol dehydrogenase, rdh1l, is essential for intestinal development and is regulated by the tumor suppressor adenomatous polyposis coli.
The Journal of biological chemistry - 26 Aug 2005
Nadauld Lincoln D, Shelton Dawne N, Chidester Stephanie, Yost H Joseph, Jones David A
Abstract excerpt
Retinoic acid (RA) is a potent signaling molecule that plays important roles in multiple and diverse developmental processes. The contribution of retinoic acid to promoting the development and differentiation of the vertebrate intestine and the factors that regulate RA production in the gut remain poorly defined. Herein, we report that the novel retinol dehydrogenase, rdh1l, is required for proper gut development...
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