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Article

Estrogen receptors orchestrate cell growth and differentiation to facilitate liver regeneration

1 Jan 2018

Abstract excerpt

Background and Aims: Improving liver regeneration (LR) capacity and thereby liver function reserve is a critical bridging strategy for managing liver failure patients. Since estrogen signaling may participate in LR, our aim was to characterize the roles of ER and ER in LR. Methods: LR capacity and estradiol levels following 2/3 rd partial hepatectomy (PHx) were compared in ER-KO or ER-KO vs. wildtype mice. The...

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PMID: 29774067
DOI: 10.7150/thno.23624

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