Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Coactivator Recruitment Is Essential for Liganded Thyroid Hormone Receptor To Initiate Amphibian Metamorphosis

17 Jun 2005

Abstract excerpt

Thyroid hormone receptors (TRs) can repress or activate target genes depending on the absence or presence of thyroid hormone (T3), respectively. This hormone-dependent gene regulation is mediated by recruitment of co-repressors in the absence of T3 and coactivators in its presence. Many TR-interacting coactivators have been characterized in vitro. In comparison, few studies have addressed the developmental roles...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Thyroid Disorders and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15964825
DOI: 10.1128/mcb.25.13.5712-5724.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Coactivator Recruitment Is Essential for Liganded Thyroid Hormone Receptor To Initiate Amphibian MetamorphosisPMID 15964825Read ↗

Tissue- and Gene-specific Recruitment of Steroid Receptor Coactivator-3 by Thyroid Hormone Receptor during DevelopmentSemantic proximity Read ↗

SRC-p300 Coactivator Complex Is Required for Thyroid Hormone-induced Amphibian MetamorphosisSemantic proximity Read ↗

A Role of Endogenous Histone Acetyltransferase Steroid Hormone Receptor Coactivator 3 in Thyroid Hormone Signaling During Xenopus Intestinal MetamorphosisSemantic proximity Read ↗

Dual Functions of Thyroid Hormone Receptors in Vertebrate Development: The Roles of Histone-Modifying Cofactor ComplexesSemantic proximity Read ↗

Role of Thyroid Hormone Receptor in Amphibian Development.Semantic proximity Read ↗

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors.Semantic proximity Read ↗

Transgenic Analysis Reveals that Thyroid Hormone Receptor Is Sufficient To Mediate the Thyroid Hormone Signal in Frog MetamorphosisSemantic proximity Read ↗

Organ-Specific Requirements for Thyroid Hormone Receptor Ensure Temporal Coordination of Tissue-Specific Transformations and Completion of Xenopus MetamorphosisSemantic proximity Read ↗

Thyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruptionSemantic proximity Read ↗

The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo.Semantic proximity Read ↗

Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development.Semantic proximity Read ↗

Role of co-regulators in metabolic and transcriptional actions of thyroid hormone.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.