Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development.

The EMBO journal - 18 Oct 2006

Havis Emmanuelle, Le Mevel Sébastien, Morvan Dubois Ghislaine, Shi De-Li, Scanlan Thomas S, Demeneix Barbara A, Sachs Laurent M

Abstract excerpt

Thyroid hormone receptors generally activate transcription of target genes in the presence of thyroid hormone (T(3)) and repress their transcription in its absence. Here, we investigated the role of unliganded thyroid hormone receptor (TR) during vertebrate development using an amphibian model. P...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Contrast Media
Share to Eye
Share to Gene Expression Regulation, Developmental

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Ligands

Share to Nuclear Proteins

Share to Receptors, Thyroid Hormone

Share to Xenopus laevis

Share to Xenopus Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 17006540
DOI: 10.1038/sj.emboj.7601356
PMCID: PMC1618110

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17006540-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unliganded thyroid hormone receptor is essential for Xenopus laevis eye development.PMID 17006540Read ↗

A role of unliganded thyroid hormone receptor in postembryonic development in Xenopus laevisSemantic proximity Read ↗

Role of Thyroid Hormone Receptor in Amphibian Development.Semantic proximity Read ↗

Life Without Thyroid Hormone ReceptorSemantic proximity Read ↗

Dual Functions of Thyroid Hormone Receptors in Vertebrate Development: The Roles of Histone-Modifying Cofactor ComplexesSemantic proximity Read ↗

An unliganded thyroid hormone receptor causes severe neurological dysfunctionSemantic proximity Read ↗

Insight into the physiological actions of thyroid hormone receptors from genetically modified mice.Semantic proximity Read ↗

NCoR1-independent mechanism plays a role in the action of the unliganded thyroid hormone receptor.Semantic proximity Read ↗

Implication of thyroid hormone signaling in neural crest cells migration: Evidence from thyroid hormone receptor beta knockdown and NH3 antagonist studies.Semantic proximity Read ↗

Unliganded thyroid hormone receptor α regulates developmental timing via gene repression in Xenopus tropicalis.Semantic proximity Read ↗

Thyroid hormone action in the absence of thyroid hormone receptor DNA-binding in vivo.Semantic proximity Read ↗

Xenopus laevis as a model for studying thyroid hormone signalling: From development to metamorphosisSemantic proximity Read ↗

Mice devoid of all known thyroid hormone receptors are viable but exhibit disorders of the pituitary-thyroid axis, growth, and bone maturation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.