Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transgenic Analysis Reveals that Thyroid Hormone Receptor Is Sufficient To Mediate the Thyroid Hormone Signal in Frog Metamorphosis

29 Sept 2004

Abstract excerpt

Thyroid hormone (T3) has long been known to be important for vertebrate development and adult organ function. Whereas thyroid hormone receptor (TR) knockout and transgenic studies of mice have implicated TR involvement in mammalian development, the underlying molecular bases for the resulting phenotypes remain to be determined in vivo, especially considering that T3 is known to have both genomic, i.e., through...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Physiological and biochemical adaptations

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Thyroid Disorders and Treatments

Source

Identifiers

PMID: 15456876
DOI: 10.1128/mcb.24.20.9026-9037.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transgenic Analysis Reveals that Thyroid Hormone Receptor Is Sufficient To Mediate the Thyroid Hormone Signal in Frog MetamorphosisPMID 15456876Read ↗

Role of Thyroid Hormone Receptor in Amphibian Development.Semantic proximity Read ↗

Thyroid hormone receptor actions on transcription in amphibia: The roles of histone modification and chromatin disruptionSemantic proximity Read ↗

Life Without Thyroid Hormone ReceptorSemantic proximity Read ↗

Organ-Specific Requirements for Thyroid Hormone Receptor Ensure Temporal Coordination of Tissue-Specific Transformations and Completion of Xenopus MetamorphosisSemantic proximity Read ↗

Xenopus metamorphosis as a model to study thyroid hormone receptor function during vertebrate developmental transitionsSemantic proximity Read ↗

Dual Functions of Thyroid Hormone Receptors in Vertebrate Development: The Roles of Histone-Modifying Cofactor ComplexesSemantic proximity Read ↗

Gene-specific changes in promoter occupancy by thyroid hormone receptor during frog metamorphosis. Implications for developmental gene regulation.Semantic proximity Read ↗

Organ‐specific effects on target binding due to knockout of thyroid hormone receptor α during Xenopus metamorphosisSemantic proximity Read ↗

Frogs model man: In vivo thyroid hormone signaling during developmentSemantic proximity Read ↗

A Rapid, Physiologic Protocol for Testing Transcriptional Effects of Thyroid-Disrupting Agents in Premetamorphic Xenopus TadpolesSemantic proximity Read ↗

Thyroid Hormone Receptor Is Essential for Larval Epithelial Apoptosis and Adult Epithelial Stem Cell Development but Not Adult Intestinal Morphogenesis during Xenopus tropicalis MetamorphosisSemantic proximity Read ↗

Identification of Direct Thyroid Hormone Response Genes Reveals the Earliest Gene Regulation Programs during Frog MetamorphosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.