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Article

Functional VEGF C-634G polymorphism is associated with development of diabetic macular edema and correlated with macular retinal thickness in type 2 diabetes.

Biochemical and biophysical research communications - 5 Aug 2005

Awata Takuya, Kurihara Susumu, Takata Nobuki, Neda Tamotsu, Iizuka Hiroyuki, Ohkubo Tomoko, Osaki Masataka, Watanabe Masaki, Nakashima Youhei, Inukai Kouichi, Inoue Ikuo, Kawasaki Izumi, Mori Keisuke, Yoneya Shin, Katayama Shigehiro

Abstract excerpt

Since vascular endothelial growth factor (VEGF) has a strong effect on induction of vascular permeability, VEGF is an attractive candidate gene for development of diabetic macular edema (ME). Among the 378 patients with type 2 diabetes studied, 203 patients had no retinopathy, 93 had non-proliferative diabetic retinopathy (NPDR), and 82 had proliferative diabetic retinopathy (PDR). ME was present in 16 patients...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15963467
DOI: 10.1016/j.bbrc.2005.05.167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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