Article
Impact of variants in the VEGF gene on progression of proliferative diabetic retinopathy.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie - 1 Jan 2009
Nakamura Shinko, Iwasaki Naoko, Funatsu Hideharu, Kitano Shigehiko, Iwamoto Yasuhiko
Abstract excerpt
BACKGROUND: The development of diabetic retinopathy is associated with the duration of diabetes and HbA1c levels. However, the familial aggregation of diabetic retinopathy is consistent with genetic susceptibility. Recently, a -634C/G polymorphism in the vascular endothelial growth factor (VEGF) gene was shown to be associated with diabetic retinopathy. To clarify the contribution of the VEGF gene in the...
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