Article
Association of VEGF gene polymorphisms with diabetic retinopathy in a south Indian cohort.
Ophthalmic genetics - 1 Mar 2008
Uthra Satagopan, Raman Rajiv, Mukesh Bickol N, Rajkumar Samuel A, Padmaja Kumari R, Paul Pradeep G, Lakshmipathy Praveena, Gnanamoorthy Perumal, Sharma Tarun, McCarty Catherine A, Kumaramanickavel Govindasamy
Abstract excerpt
BACKGROUND: Polymorphisms in vascular endothelial growth factor (VEGF) gene have been associated with diabetic retinopathy (DR) in various populations. A promoter polymorphism and a 3'UTR variation are studied for association with DR. MATERIALS AND METHODS: Type 2 diabetic patients with and without retinopathy were recruited. The -634C/G and 936C/T polymorphisms were genotyped by direct sequencing and their...
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