Article
Review article: practical management of inflammatory bowel disease patients taking immunomodulators.
Alimentary pharmacology & therapeutics - 1 Jul 2005
Siegel C A, Sands B E
Abstract excerpt
Azathioprine, mercaptopurine, methotrexate, ciclosporin and tacrolimus all have their respective niches in the treatment of inflammatory bowel disease. These immunomodulators are potent and effective medications; however, they potentially have serious toxicity. To maximize benefit and minimize risk, clinicians must understand the mechanism of action, appropriate indications, range of toxicity and proper dosing of...
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