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Article

Therapeutic drug monitoring in patients with inflammatory bowel disease.

World journal of gastroenterology - 7 Apr 2014

Yarur Andres J, Abreu Maria T, Deshpande Amar R, Kerman David H, Sussman Daniel A

Abstract excerpt

Thiopurine analogs and anti-tumor necrosis factor (TNF) agents have dramatically changed the therapeutics of inflammatory bowel diseases (IBD), improving short and long-term outcomes. Unfortunately some patients do not respond to therapy and others lose response over time. The pharmacokinetic properties of these drugs are complex, with high inter-patient variability. Thiopurine analogs are metabolized through a...

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Identifiers

PMID: 24707130
DOI: 10.3748/wjg.v20.i13.3475
PMCID: PMC3974514

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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