Article
Normal ICOS, ICOSL and AID alleles in Danish patients with common variable immunodeficiency.
Scandinavian journal of immunology - 1 Jun 2005
Ohm-Laursen L, Schjebel L, Jacobsen K, Permin H, Svejgaard A, Barington T
Abstract excerpt
Common variable immunodeficiency, CVID, is a primary antibody deficiency characterized by decreased levels of serum immunoglobulin G (IgG), decreased IgA and/or IgM and recurrent infections. It is assumed to be heterogeneous group of disorders caused by different genetic defects. Some patients have decreased levels of class switched memory B cells and/or decreased levels of somatic hypermutation which points to...
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