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Article

Polymorphisms in chemokine receptor genes and susceptibility to Kawasaki disease.

Clinical and experimental immunology - 1 Oct 2007

Breunis W B, Biezeveld M H, Geissler J, Kuipers I M, Lam J, Ottenkamp J, Hutchinson A, Welch R, Chanock S J, Kuijpers T W

Abstract excerpt

Kawasaki disease (KD) is an acute vasculitis occurring in young children. Its aetiology is unknown, but an infectious agent is assumed. Increased levels of proinflammatory cytokines and chemokines have been reported in KD. Genetic variation in these genes and the receptors for these genes could influence the regulation of cytokines and chemokines. In a case-control study of 170 Dutch Caucasian KD patients and 300...

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Source

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Identifiers

PMID: 17672867
DOI: 10.1111/j.1365-2249.2007.03457.x
PMCID: PMC2219275

Genes

CCR5
CCR2
CCR3
CXCR1
CXCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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