Article
Association of CCR2-CCR5 haplotypes and CCL3L1 copy number with Kawasaki Disease, coronary artery lesions, and IVIG responses in Japanese children.
PloS one - 7 Jul 2010
Mamtani Manju, Matsubara Tomoyo, Shimizu Chisato, Furukawa Susumu, Akagi Teiji, Onouchi Yoshihiro, Hata Akira, Fujino Akihiro, He Weijing, Ahuja Sunil K, Burns Jane C
Abstract excerpt
BACKGROUND: The etiology of Kawasaki Disease (KD) is enigmatic, although an infectious cause is suspected. Polymorphisms in CC chemokine receptor 5 (CCR5) and/or its potent ligand CCL3L1 influence KD susceptibility in US, European and Korean populations. However, the influence of these variations on KD susceptibility, coronary artery lesions (CAL) and response to intravenous immunoglobulin (IVIG) in Japanese...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
