Article
Generation of genetically altered mouse models for aging studies.
Experimental and molecular pathology - 1 Feb 2002
Treuting P M, Hopkins H C, Ware C A, Rabinovitch P R, Ladiges W C
Abstract excerpt
A number of mouse models have been identified and are being used for aging and age-associated disease research. However, the use of the genetically manipulated mouse model is still a relatively untapped resource for the study of the biology of aging. Genetically altered mice can be powerful tools for biology of aging research because gene expression can be controlled and correlated with established biomarkers....
Topics
- Aging
- Animals
- Mice
- Mice, Transgenic
- Microinjections
- Models, Animal
- Phenotype
- Stem Cells