Article
Genetic mapping of canine multiple system degeneration and ectodermal dysplasia loci.
The Journal of heredity - 1 Jan 2005
O'Brien Dennis P, Johnson Gary S, Schnabel Robert D, Khan Shahnawaz, Coates Joan R, Johnson Gayle C, Taylor Jeremy F
Abstract excerpt
We characterized a movement disorder of Chinese Crested dogs clinically and pathologically indistinguishable from canine multiple system degeneration (CMSD) previously recognized in Kerry Blue Terriers. This fatal disease segregated as an autosomal recessive in a 51-dog pedigree of both breeds and their crosses. The occurrence of affected dogs among first-generation crosses demonstrated that the mutations causing...
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