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Article

Genome-wide association studies for multiple diseases of the German Shepherd Dog.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2012

Tsai Kate L, Noorai Rooksana E, Starr-Moss Alison N, Quignon Pascale, Rinz Caitlin J, Ostrander Elaine A, Steiner Jörg M, Murphy Keith E, Clark Leigh Anne

Abstract excerpt

The German Shepherd Dog (GSD) is a popular working and companion breed for which over 50 hereditary diseases have been documented. Herein, SNP profiles for 197 GSDs were generated using the Affymetrix v2 canine SNP array for a genome-wide association study to identify loci associated with four diseases: pituitary dwarfism, degenerative myelopathy (DM), congenital megaesophagus (ME), and pancreatic acinar atrophy...

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Identifiers

PMID: 22105877
DOI: 10.1007/s00335-011-9376-9
PMCID: PMC3509149

Genes

LHX3
SOD1

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