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Article

A canine DNM1 mutation is highly associated with the syndrome of exercise-induced collapse.

Nature genetics - 1 Oct 2008

Patterson Edward E, Minor Katie M, Tchernatynskaia Anna V, Taylor Susan M, Shelton G Diane, Ekenstedt Kari J, Mickelson James R

Abstract excerpt

Labrador retrievers are the most common dog breed in the world, with over 200,000 new kennel club registrations per year. The syndrome of exercise-induced collapse (EIC) in this breed is manifested by muscle weakness, incoordination and life-threatening collapse after intense exercise. Using a genome-wide microsatellite marker scan for linkage in pedigrees, we mapped the EIC locus to canine chromosome 9. We then...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18806795
DOI: 10.1038/ng.224

Genes

DNM1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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