Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An association between the matrix metalloproteinase 1 promoter gene polymorphism and lymphnode metastasis in breast cancer.

Journal of experimental & clinical cancer research : CR - 1 Mar 2004

Przybylowska K, Zielinska J, Zadrozny M, Krawczyk T, Kulig A, Wozniak P, Rykala J, Kolacinska A, Morawiec Z, Drzewoski J, Blasiak J

Abstract excerpt

A single guanine insertion (1G/2G polymorphism) in the promoter of the matrix metalloproteinase (MMP-1) gene creates a binding site for the transcription factor and may affect the level of transcription of MMP-1. An elevated level of MMP-1 in cancer cells may facilitate their invasion and contribute to metastasis. To evaluate the contribution of 1G/2G polymorphism in the development and/or progression of breast...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease Progression

Share to Matrix Metalloproteinase 1

Share to Neoplasm Metastasis

Share to Polymerase Chain Reaction

Share to Prognosis

Share to Promoter Regions, Genetic

Source

Identifiers

PMID: 15149160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An association between the matrix metalloproteinase 1 promoter gene polymorphism and lymphnode metastasis in breast cancer.PMID 15149160Read ↗

Matrix metalloproteinase-1 promoter polymorphism 1G/2G is correlated with colorectal cancer invasiveness.Semantic proximity Read ↗

Polymorphisms of the promoter regions of matrix metalloproteinases genes MMP-1 and MMP-9 in breast cancer.Semantic proximity Read ↗

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter in endometrial carcinomas.Semantic proximity Read ↗

Rapid genotype analysis of the matrix metalloproteinase-1 gene 1G/2G polymorphism that is associated with risk of cancer.Semantic proximity Read ↗

Analysis of matrix metalloproteinase-1 gene polymorphisms and expression in benign and malignant breast tumors.Semantic proximity Read ↗

A functional polymorphism in the matrix metalloproteinase-1 gene promoter is associated with susceptibility and aggressiveness of head and neck cancer.Semantic proximity Read ↗

The Association of Matrix Metalloproteinase-1 Promoter Polymorphisms with Breast Cancer.Semantic proximity Read ↗

A single nucleotide polymorphism in the MMP-1 promoter is correlated with histological differentiation of gastric cancer.Semantic proximity Read ↗

The influence of interstitial collagenase-1 genotype polymorphism on colorectal cancer risk in Iranian population.Semantic proximity Read ↗

A single nucleotide polymorphism in the matrix metalloproteinase-1 promoter enhances lung cancer susceptibility.Semantic proximity Read ↗

Matrix metalloproteinase-1 promoter polymorphism and lung cancer risk.Semantic proximity Read ↗

Matrix metalloproteinase-2 polymorphisms and breast cancer susceptibility.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.