Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human Cytomegalovirus UL130 Protein Promotes Endothelial Cell Infection through a Producer Cell Modification of the Virion

15 Jun 2005

Abstract excerpt

Human cytomegalovirus (HCMV) growth in endothelial cells (EC) requires the expression of the UL131A-128 locus proteins. In this study, the UL130 protein (pUL130), the product of the largest gene of the locus, is shown to be a luminal glycoprotein that is inefficiently secreted from infected cells but is incorporated into the virion envelope as a Golgi-matured form. To investigate the mechanism of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Neutrophil, Myeloperoxidase and Oxidative Mechanisms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15956581
DOI: 10.1128/jvi.79.13.8361-8373.2005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human Cytomegalovirus UL130 Protein Promotes Endothelial Cell Infection through a Producer Cell Modification of the VirionPMID 15956581Read ↗

Human Cytomegalovirus UL131-128 Genes Are Indispensable for Virus Growth in Endothelial Cells and Virus Transfer to LeukocytesSemantic proximity Read ↗

Role of human cytomegalovirus UL131A in cell type-specific virus entry and releaseSemantic proximity Read ↗

Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropismSemantic proximity Read ↗

UL74 of Human Cytomegalovirus Contributes to Virus Release by Promoting Secondary Envelopment of VirionsSemantic proximity Read ↗

Characterization of the Human Cytomegalovirus gH/gL/UL128-131 Complex That Mediates Entry into Epithelial and Endothelial CellsSemantic proximity Read ↗

A human cytomegalovirus gO-null mutant fails to incorporate gH/gL into the virion envelope and is unable to enter fibroblasts and epithelial and endothelial cells.Semantic proximity Read ↗

Human Cytomegalovirus <i>UL135</i> and <i>UL136</i> Genes Are Required for Postentry Tropism in Endothelial CellsSemantic proximity Read ↗

Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implicationsSemantic proximity Read ↗

Human cytomegalovirus entry into epithelial and endothelial cells depends on genes UL128 to UL150 and occurs by endocytosis and low-pH fusion.Semantic proximity Read ↗

An Endothelial Cell-Specific Requirement for the <i>UL133-UL138</i> Locus of Human Cytomegalovirus for Efficient Virus MaturationSemantic proximity Read ↗

Impact of sequence variation in the UL128 locus on production of human cytomegalovirus in fibroblast and epithelial cells.Semantic proximity Read ↗

Human Cytomegalovirus UL131 Open Reading Frame Is Required for Epithelial Cell TropismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.