Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implications

18 Jan 2010

Abstract excerpt

Human cytomegalovirus (HCMV) has been routinely isolated from and propagated in vitro in human embryonic lung fibroblast (HELF) cell cultures, while in vivo it is known to infect predominantly endothelial and epithelial cells. In recent years, genetic determinants of the HCMV tropism for endothelial/epithelial cells were identified in the UL131A/UL130/UL128 locus of HCMV genome of wild-type strains. UL131A-UL128...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to Herpesvirus Infections and Treatments
Share to Parvovirus B19 Infection Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 20084641
DOI: 10.1002/rmv.645

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human cytomegalovirus tropism for endothelial/epithelial cells: scientific background and clinical implicationsPMID 20084641Read ↗

Human Cytomegalovirus Cell Tropism and Host Cell ReceptorsSemantic proximity Read ↗

Role of human cytomegalovirus UL131A in cell type-specific virus entry and releaseSemantic proximity Read ↗

Endothelial cells in human cytomegalovirus infection: One host cell out of many or a crucial target for virus spread?Semantic proximity Read ↗

Human cytomegalovirus virion protein complex required for epithelial and endothelial cell tropismSemantic proximity Read ↗

Mutational mapping of pUL131A of human cytomegalovirus emphasizes its central role for endothelial cell tropism.Semantic proximity Read ↗

Human Cytomegalovirus UL131-128 Genes Are Indispensable for Virus Growth in Endothelial Cells and Virus Transfer to LeukocytesSemantic proximity Read ↗

Neutralization of Human Cytomegalovirus Entry into Fibroblasts and Epithelial CellsSemantic proximity Read ↗

Influence of human cytomegalovirus glycoprotein O polymorphism on the inhibitory effect of soluble forms of trimer- and pentamer-specific entry receptorsSemantic proximity Read ↗

Human Cytomegalovirus Tropism for Endothelial Cells: Not All Endothelial Cells Are Created EqualSemantic proximity Read ↗

HCMV Spread and Cell Tropism are Determined by Distinct Virus PopulationsSemantic proximity Read ↗

Dendritic-cell infection by human cytomegalovirus is restricted to strains carrying functional UL131–128 genes and mediates efficient viral antigen presentation to CD8+ T cellsSemantic proximity Read ↗

Characterization of the Human Cytomegalovirus gH/gL/UL128-131 Complex That Mediates Entry into Epithelial and Endothelial CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.