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Article

Paclitaxel resistance in cells with reduced beta-tubulin.

Biochimica et biophysica acta - 30 Jun 2005

Wang Yaqing, Cabral Fernando

Abstract excerpt

We previously described the isolation of colcemid resistant Chinese hamster ovary cell lines containing alpha- and beta-tubulin mutations that increase microtubule assembly and stability. By analyzing colcemid sensitive revertants from one of the beta-tubulin mutants, we now find that loss or inactivation of the mutant allele represents the most common mechanism of reversion. Consistent with this loss, the...

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Identifiers

PMID: 15950754
DOI: 10.1016/j.bbamcr.2004.12.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Paclitaxel resistance in cells with reduced beta-tubulin.PMID 15950754Read ↗

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