Article
The C3435T polymorphism of MDR1 and susceptibility to adult glioma.
Neuroepidemiology - 1 Jan 2005
Miller Katie L, Kelsey Karl T, Wiencke John K, Moghadassi Michelle, Miike Rei, Liu Mei, Wrensch Margaret
Abstract excerpt
INTRODUCTION: The multidrug resistance-1 (MDR1) gene encodes a pump that prevents potentially carcinogenic substances from crossing the blood-brain barrier. We compare adult glioma cases and controls for the C3435T polymorphism that has been associated with reduced MDR1 expression. METHODS: Adult glioma in the San Francisco Bay area and population-based controls were identified between 1991-1994 and 1997-1999....
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