Article
Evolutionary diversity and potential recombinogenic role of integration targets of Non-LTR retrotransposons.
Molecular biology and evolution - 1 Oct 2005
Gentles Andrew J, Kohany Oleksiy, Jurka Jerzy
Abstract excerpt
Short interspersed elements (SINEs) make up a significant fraction of total DNA in mammalian genomes, providing a rich substrate for chromosomal rearrangements by SINE-SINE recombinations. Proliferation of mammalian SINEs is mediated primarily by long interspersed element 1 (L1) non-long terminal repeat retrotransposons that preferentially integrate at DNA sequence targets with an average length of approximately...
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