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Article

Insertion of Telomeric Repeats in the Human and Horse Genomes: An Evolutionary Perspective.

International journal of molecular sciences - 18 Apr 2020

Santagostino Marco, Piras Francesca M, Cappelletti Eleonora, Del Giudice Simone, Semino Ornella, Nergadze Solomon G, Giulotto Elena

Abstract excerpt

Interstitial telomeric sequences (ITSs) are short stretches of telomeric-like repeats (TTAGGG)n at nonterminal chromosomal sites. We previously demonstrated that, in the genomes of primates and rodents, ITSs were inserted during the repair of DNA double-strand breaks. These conclusions were derived from sequence comparisons of ITS-containing loci and ITS-less orthologous loci in different species. To our...

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Source

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Identifiers

PMID: 32325780
DOI: 10.3390/ijms21082838
PMCID: PMC7215372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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