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Article

Alpha-synuclein phosphorylation enhances eosinophilic cytoplasmic inclusion formation in SH-SY5Y cells.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 8 Jun 2005

Smith Wanli W, Margolis Russell L, Li Xiaojie, Troncoso Juan C, Lee Michael K, Dawson Valina L, Dawson Ted M, Iwatsubo Takashi, Ross Christopher A

Abstract excerpt

Parkinson's disease (PD) is a neurodegenerative disorder characterized by selective loss of dopaminergic neurons and the presence of Lewy bodies. Previous reports have shown that alpha-synuclein deposited in brain tissue from individuals with synucleinopathy is extensively phosphorylated at Ser-1...

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Identifiers

PMID: 15944382
DOI: 10.1523/JNEUROSCI.0482-05.2005
PMCID: PMC6724982

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15944382-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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