Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast.

International journal of oncology - 1 Jul 2005

Schagdarsurengin Undraga, Seidel Claudia, Ulbrich Eva J, Kölbl Heinz, Dittmer Jürgen, Dammann Reinhard

Abstract excerpt

The tumor suppressor gene RASSF1A is inactivated or mutated in different tumor entities including breast cancer. The frequency of the genomic variants of RASSF1A in patients with breast tumors has not been evaluated. We studied the association between ten nucleotide polymorphisms of RASSF1A and the risk of breast cancer in 178 cases with tumorous alterations of mammary tissue (including 141 carcinomas and 37...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Breast
Share to Breast Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Homozygote

Share to Polymorphism, Single-Stranded Conformational

Share to Serine

Share to Temperature

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 15942659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A polymorphism at codon 133 of the tumor suppressor RASSF1A is associated with tumorous alteration of the breast.PMID 15942659Read ↗

RASSF1A polymorphism A133S is associated with early onset breast cancer in BRCA1/2 mutation carriers.Semantic proximity Read ↗

Single nucleotide polymorphism at codon 133 of the RASSF1 gene is preferentially associated with human lung adenocarcinoma risk.Semantic proximity Read ↗

RASSF1A polymorphism in familial breast cancer.Semantic proximity Read ↗

Association between RASSF1A Ala133Ser polymorphism and cancer susceptibility: a meta-analysis involving 8,892 subjects.Semantic proximity Read ↗

RASSF1A Ala133Ser polymorphism is associated with increased susceptibility to hepatocellular carcinoma in a Turkish population.Semantic proximity Read ↗

Hypermethylation of the cpG island of Ras association domain family 1A (RASSF1A), a putative tumor suppressor gene from the 3p21.3 locus, occurs in a large percentage of human breast cancers.Semantic proximity Read ↗

Aberrant methylation of RASSF1A in plasma DNA before breast cancer diagnosis in the Breast Cancer Family Registry.Semantic proximity Read ↗

C to A single nucleotide polymorphism in intron 18 of the human MST1R (RON) gene that maps at 3p21.3.Semantic proximity Read ↗

A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma.Semantic proximity Read ↗

A role for the RASSF1A tumor suppressor in the regulation of tubulin polymerization and genomic stability.Semantic proximity Read ↗

Gly322Asp and Asn127Ser single nucleotide polymorphisms (SNPs) of hMSH2 mismatch repair gene and the risk of triple-negative breast cancer in Polish women.Semantic proximity Read ↗

Molecular abnormalities associated with secretory carcinomas of the breast.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.