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Article

Genome amplification of single sperm using multiple displacement amplification.

Nucleic acids research - 7 Jun 2005

Jiang Zhengwen, Zhang Xingqi, Deka Ranjan, Jin Li

Abstract excerpt

Sperm typing is an effective way to study recombination rate on a fine scale in regions of interest. There are two strategies for the amplification of single meiotic recombinants: repulsion-phase allele-specific PCR and whole genome amplification (WGA). The former can selectively amplify single recombinant molecules from a batch of sperm but is not scalable for high-throughput operation. Currently, primer...

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Identifiers

PMID: 15942023
DOI: 10.1093/nar/gni089
PMCID: PMC1143700

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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