Article
DHPLC analysis of the matrix metalloproteinase-1 promoter 1G/2G polymorphism that can be easily used to screen large population.
Journal of biochemical and biophysical methods - 30 Jun 2005
Xu Enping, Lai Maode, Lv Bingjian, Xing Xiaoming, Huang Qiong, Ma Yu, Wang Wei
Abstract excerpt
Matrix metalloproteinase-1 has been shown to play an important role in all stages of cancer initiation, invasion, and metastasis. The 1G/2G single nucleotide polymorphism (SNP) at -1607 to -1608 creates an Ets binding site and elevates the rate of transcription. Moreover, the presence of the 2G a...
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