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Article

Characteristic defects in neural crest cell-specific Galphaq/Galpha11- and Galpha12/Galpha13-deficient mice.

Developmental biology - 1 Jun 2005

Dettlaff-Swiercz Dagmara A, Wettschureck Nina, Moers Alexandra, Huber Katrin, Offermanns Stefan

Abstract excerpt

The endothelin/endothelin receptor system plays a critical role in the differentiation and terminal migration of particular neural crest cell subpopulations. Targeted deletion of the G-protein-coupled endothelin receptors ET(A) and ET(B) was shown to result in characteristic developmental defects of derivatives of cephalic and cardiac neural crest and of neural crest-derived melanocytes and enteric neurons,...

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Source

Identifiers

PMID: 15936338
DOI: 10.1016/j.ydbio.2005.03.006

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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