Article
High-throughput gender determination using automated denaturant gel capillary electrophoresis.
Electrophoresis - 1 Jun 2005
Hinselwood David C, Warren David J, Ekstrøm Per O
Abstract excerpt
Sex determination of anonymous samples is a requirement before analysis of DNA variation on X or Y chromosomes. Based on this, we designed a method for screening samples on different DNA capillary sequencing instruments with a sensitivity that is able to quantify sex chromosome abnormalities. The two different amelogenin alleles sited on the X and Y chromosomes were polymerase chain reaction amplified with the...
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