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Article

Functional disconnectivity in subjects at high genetic risk of schizophrenia.

Brain : a journal of neurology - 1 Sept 2005

Whalley Heather C, Simonotto Enrico, Marshall Ian, Owens David G C, Goddard Nigel H, Johnstone Eve C, Lawrie Stephen M

Abstract excerpt

Schizophrenia is a highly heritable psychotic disorder. It has been suggested that deficits of the established state arise from abnormal interactions between brain regions. We sought to examine whether such connectivity abnormalities would be present in subjects at high genetic risk for the disorder. Functional connectivity analysis was carried out on functional MRI images from 21 controls and 69 high risk...

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Identifiers

PMID: 15930046
DOI: 10.1093/brain/awh556

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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