Article
The association of polygenic risk for schizophrenia, bipolar disorder, and depression with neural connectivity in adolescents and young adults: examining developmental and sex differences.
Translational psychiatry - 14 Jan 2021
Meyers J L, Chorlian D B, Bigdeli T B, Johnson E C, Aliev F, Agrawal A, Almasy L, Anokhin A, Edenberg H J, Foroud T, Goate A, Kamarajan C, Kinreich S, Nurnberger J, Pandey A K, Pandey G, Plawecki M H, Salvatore J E, Zhang J, Fanous A, Porjesz B
Abstract excerpt
Neurodevelopmental abnormalities in neural connectivity have been long implicated in the etiology of schizophrenia (SCZ); however, it remains unclear whether these neural connectivity patterns are associated with genetic risk for SCZ in unaffected individuals (i.e., an absence of clinical features of SCZ or a family history of SCZ). We examine whether polygenic risk scores (PRS) for SCZ are associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.