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Article

Cytokine-driven cell cycling is mediated through Cdc25A.

The Journal of cell biology - 6 Jun 2005

Khaled Annette R, Bulavin Dmitry V, Kittipatarin Christina, Li Wen Qing, Alvarez Michelle, Kim Kyungjae, Young Howard A, Fornace Albert J, Durum Scott K

Abstract excerpt

Lymphocytes are the central mediators of the immune response, requiring cytokines for survival and proliferation. Survival signaling targets the Bcl-2 family of apoptotic mediators, however, the pathway for the cytokine-driven proliferation of lymphocytes is poorly understood. Here we show that cytokine-induced cell cycle progression is not solely dependent on the synthesis of cyclin-dependent kinases (Cdks) or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15928203
DOI: 10.1083/jcb.200409099
PMCID: PMC2171622

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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