Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

MrgX is not essential for cell growth and development in the mouse.

Molecular and cellular biology - 1 Jun 2005

Tominaga Kaoru, Matzuk Martin M, Pereira-Smith Olivia M

Abstract excerpt

MRGX is one of the members of MORF4/MRG family of transcriptional regulators, which are involved in cell growth regulation and cellular senescence. We have shown that MRGX and MRG15 associate with Rb in nucleoprotein complexes and regulate B-myb promoter activity. To elucidate the functions of MRGX and to explore its potential role in modulating cell growth in vivo, we have generated MrgX-deficient mice....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Fractionation
Share to Chromosomal Proteins, Non-Histone
Share to Embryonic Development

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Targeting

Share to Genes, cdc

Share to Macromolecular Substances

Share to Retinoblastoma Protein

Share to Tissue Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 15923606
DOI: 10.1128/MCB.25.12.4873-4880.2005
PMCID: PMC1140578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

MrgX is not essential for cell growth and development in the mouse.PMID 15923606Read ↗

MRG15 activates the B-myb promoter through formation of a nuclear complex with the retinoblastoma protein and the novel protein PAM14.Semantic proximity Read ↗

Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster.Semantic proximity Read ↗

MRG proteins are shared by multiple protein complexes with distinct functionsSemantic proximity Read ↗

Targeted inactivation of myogenic factor genes reveals their role during mouse myogenesis: a review.Semantic proximity Read ↗

Rbm15 Modulates Notch-Induced Transcriptional Activation and Affects Myeloid DifferentiationSemantic proximity Read ↗

Serum response factor is essential for mesoderm formation during mouse embryogenesis.Semantic proximity Read ↗

Muscle differentiation is antagonized by SOX15, a new member of the SOX protein family.Semantic proximity Read ↗

Mice lacking dystrophin or alpha sarcoglycan spontaneously develop embryonal rhabdomyosarcoma with cancer-associated p53 mutations and alternatively spliced or mutant Mdm2 transcripts.Semantic proximity Read ↗

Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.Semantic proximity Read ↗

Loss of the mammalian DREAM complex deregulates chondrocyte proliferation.Semantic proximity Read ↗

Embryo Mortality in Isg15−/− Mice Is Exacerbated by Environmental Stress1Semantic proximity Read ↗

The Receptor Tyrosine Kinase Ror2 Associates with the Melanoma-associated Antigen (MAGE) Family Protein Dlxin-1 and Regulates Its Intracellular DistributionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.