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Article

Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.

Scientific reports - 27 Jan 2017

Henrich Sarah Marie, Usadel Clemens, Werwein Eugen, Burdova Kamila, Janscak Pavel, Ferrari Stefano, Hess Daniel, Klempnauer Karl-Heinz

Abstract excerpt

B-Myb, a highly conserved member of the Myb transcription factor family, is expressed ubiquitously in proliferating cells and controls the cell cycle dependent transcription of G2/M-phase genes. Deregulation of B-Myb has been implicated in oncogenesis and loss of genomic stability. We have identified B-Myb as a novel interaction partner of the Mre11-Rad50-Nbs1 (MRN) complex, a key player in the repair of DNA...

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Identifiers

PMID: 28128338
DOI: 10.1038/srep41663
PMCID: PMC5269693

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Interplay with the Mre11-Rad50-Nbs1 complex and phosphorylation by GSK3β implicate human B-Myb in DNA-damage signaling.PMID 28128338Read ↗

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