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Article

Human ganglion cells express the alpha-2 adrenergic receptor: relevance to neuroprotection

27 May 2005

Abstract excerpt

BACKGROUND/AIM: Alpha-2alpha adrenergic receptor (alpha(2)-AR) agonists are thought to be neuroprotective, preventing retinal ganglion cell death independent of pressure reduction. Previous studies have identified alpha(2)-ARs in rat retina. The authors aimed to demonstrate the presence and localisation of alpha(2)-ARs in human and rat retina and on the rat retinal ganglion cell line, RGC-5. METHODS: Seven...

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PMID: 15923515
DOI: 10.1136/bjo.2004.053025

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