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Localization of Alpha-2 Adrenergic Receptors in the Human Eye

10 Dec 2009

Abstract excerpt

To elucidate sites of the action of alpha-2 adrenergic drugs, we localized binding sites for a potent alpha-2 adrenergic agonist, UK-14,304, in sections of the human cadaveric eye by an in vitro ligand-binding technique and autoradiography. Its specific binding sites were found in the iris epithelium and ciliary epithelium at a high level, and also in the ciliary muscle, retina, retinal pigment epithelium (and/or...

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PMID: 1359487
DOI: 10.1159/000267170

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