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Article

Potential role of P2X7 receptor in neurodegenerative processes in a murine model of glaucoma

15 May 2019

Abstract excerpt

Glaucoma is a common cause of visual impairment and blindness, characterized by retinal ganglion cell (RGC) death. The mechanisms that trigger the development of glaucoma remain unknown and have gained significant relevance in the study of this neurodegenerative disease. P2X7 purinergic receptors (P2X7R) could be involved in the regulation of the synaptic transmission and neuronal death in the retina through...

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Share to Adenosine and Purinergic Signaling
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PMID: 31102752
DOI: 10.1016/j.brainresbull.2019.05.006

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