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Article

Glaucoma, apoptosis, and neuroprotection

1 Apr 1997

Abstract excerpt

The demise of the retinal ganglion cell represents the final common pathway of glaucomatous vision loss. Various studies demonstrate that ganglion cells die by the mechanism of apoptosis in conditions such as experimental animal models of glaucoma and optic nerve transection, and in human glaucoma. Apoptosis is a basic cell death mechanism noted in a number of neurodegenerative conditions. It constitutes a...

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PMID: 10168354
DOI: 10.1097/00055735-199704000-00006

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