Article
A physical interaction between Gar1p and Rnt1pi is required for the nuclear import of H/ACA small nucleolar RNA-associated proteins.
Molecular and cellular biology - 1 Jul 2002
Tremblay Annie, Lamontagne Bruno, Catala Mathieu, Yam Yeung, Larose Stephanie, Good Liam, Elela Sherif Abou
Abstract excerpt
During rRNA biogenesis, multiple RNA and protein substrates are modified and assembled through the coordinated activity of many factors. In Saccharomyces cerevisiae, the double-stranded RNA nuclease Rnt1p and the H/ACA snoRNA pseudouridylase complex participate in the transformation of the nascent pre-rRNA transcript into 35S pre-rRNA. Here we demonstrate the binding of a component of the H/ACA complex (Gar1p) to...
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