Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Skewed X chromosome inactivation and early-onset breast cancer.

Journal of medical genetics - 1 Jan 2006

Struewing J P, Pineda M A, Sherman M E, Lissowska J, Brinton L A, Peplonska B, Bardin-Mikolajczak A, Garcia-Closas M

Abstract excerpt

BACKGROUND: Skewed X chromosome inactivation may be more common in women with epithelial ovarian cancer and early-onset breast cancer. We tested this hypothesis in a group of 235 breast cancer patients and 253 controls (mean age 45.8 years) from a larger population based case control study. METHODS: We measured X chromosome inactivation with the AR gene assay in lymphocyte DNA digested with the methylation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to X Chromosome Inactivation
Share to Age of Onset

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Breast Neoplasms

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Source

Open in PubMed Open full text

Identifiers

PMID: 15923273
DOI: 10.1136/jmg.2005.033134
PMCID: PMC1876702

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Skewed X chromosome inactivation and early-onset breast cancer.PMID 15923273Read ↗

Skewed X chromosome inactivation and breast and ovarian cancer status: evidence for X-linked modifiers of BRCA1.Semantic proximity Read ↗

High incidence of skewed X chromosome inactivation in young patients with familial non-BRCA1/BRCA2 breast cancer: Table 1Semantic proximity Read ↗

Skewed X inactivation in healthy individuals and in different diseasesSemantic proximity Read ↗

Diminished sex hormone levels influence the risk of skewed X chromosome inactivationSemantic proximity Read ↗

Skewed X inactivation in X-linked disorders.Semantic proximity Read ↗

Age-associated skewing of X-inactivation ratios of blood cells in normal females: a candidate-gene analysis approach.Semantic proximity Read ↗

The dynamics of X‐inactivation skewing as women ageSemantic proximity Read ↗

Skewed X-chromosome inactivation is a common feature of X-linked mental retardation disorders.Semantic proximity Read ↗

Transmission-ratio distortion of X chromosomes among male offspring of females with skewed X-inactivation.Semantic proximity Read ↗

Skewness of X-chromosome inactivation increases with age and varies across birth cohorts in elderly Danish womenSemantic proximity Read ↗

Nonrandom X Chromosome Inactivation Detection.Semantic proximity Read ↗

X-chromosome inactivation patterns depend on age and tissue but not conception method in humansSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.