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Smoky coal exposure, NBS1 polymorphisms, p53 protein accumulation, and lung cancer risk in Xuan Wei, China.

Lung cancer (Amsterdam, Netherlands) - 1 Sept 2005

Lan Qing, Shen Min, Berndt Sonja I, Bonner Matthew R, He Xingzhou, Yeager Meredith, Welch Robert, Keohavong Phouthone, Donahue Mark, Hainaut Pierre, Chanock Stephen

Abstract excerpt

Lung cancer rates in Xuan Wei County are among the highest in China and have been associated with exposure to indoor smoky coal emissions that contain high levels of polycyclic aromatic hydrocarbons (PAHs). The NBS1 gene product participates in DNA double-strand break repair and DNA damage-induced checkpoint activation, which are critical for maintaining genomic integrity. The p53 tumor suppressor gene is known...

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PMID: 15921821
DOI: 10.1016/j.lungcan.2005.04.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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