Article
No evidence for genetically determined alteration in insulin secretion or sensitivity predisposing to type 1 diabetes: a study of identical twins.
Diabetes care - 1 Jun 2005
Hawa Mohammed I, Bonfanti Riccardo, Valeri Christina, Delli Castelli Michela, Beyan Huriya, Leslie R David G
Abstract excerpt
OBJECTIVE: To determine whether inherited changes in insulin secretion or sensitivity could predispose to type 1 diabetes, we studied identical twins of type 1 diabetic patients. RESEARCH DESIGN AND METHODS: We studied prospectively a consecutive series of 27 identical twins of patients with type 1 diabetes who were initially nondiabetic, as well as 14 control subjects, over a period of 18 years. Of these 27...
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