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Article

Different pathophysiology of impaired glucose tolerance in first-degree relatives of individuals with type 2 diabetes mellitus.

Metabolism: clinical and experimental - 1 May 2009

Emerson Peter, Van Haeften Timon W, Pimenta Walkyria, Plummer Elena, Woerle Hans J, Mitrakou Asimina, Szoke Ervin, Gerich John, Meyer Christian

Abstract excerpt

To assess whether an increased genetic predisposition for type 2 diabetes mellitus (T2DM) influences the contributions of insulin resistance and impaired insulin secretion to impaired glucose tolerance (IGT), 437 subjects not known to have T2DM underwent an oral glucose tolerance test and a 3-hour hyperglycemic clamp. Plasma insulin responses and insulin sensitivity were compared between all subjects (unselected...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19375581
DOI: 10.1016/j.metabol.2008.12.004
PMCID: PMC2713184

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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