Article
Defective infectious particles and rare packaged genomes produced by cells carrying terminal-repeat-negative epstein-barr virus.
Journal of virology - 1 Jun 2005
Feederle R, Shannon-Lowe C, Baldwin G, Delecluse H J
Abstract excerpt
The Epstein-Barr virus (EBV) lytic program includes lytic viral DNA replication and the production of a viral particle into which the replicated viral DNA is packaged. The terminal repeats (TRs) located at the end of the linear viral DNA have been identified as the packaging signals. A TR-negative (TR(-)) mutant therefore provides an appropriate tool to analyze the relationships between EBV DNA packaging and...
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