Article
An Epstein-Barr Virus Mutant Produces Immunogenic Defective Particles Devoid of Viral DNA
13 Dec 2012
Abstract excerpt
Virus-like particles (VLPs) from hepatitis B and human papillomaviruses have been successfully used as preventative vaccines against these infectious agents. These VLPs consist of a self-associating capsid polymer formed from a single structure protein and are devoid of viral DNA. Since virions from herpesviruses consist of a large number of molecules of viral and cellular origin, generating VLPs from a subset of...
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