Article
Two new mouse mutants with vestibular defects that map to the highly mutable locus on chromosome 4.
International journal of audiology - 1 Mar 2005
Hawker Kelvin, Fuchs Helmut, Angelis Martin Hrabéde, Steel Karen P
Abstract excerpt
The purpose of this study was to characterise two new mouse mutants, carousel, and whirligig. Both were derived from a large-scale mutagenesis programme which screened for dominantly inherited mutations that cause hearing impairments and balance defects. Genetic mapping placed both mutations on the proximal region of chromosome 4. Paint-filling and clearing techniques revealed abnormalities of the lateral...
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