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Article

Novel candidate genes for vestibular function identified through GWAS in the hybrid mouse diversity panel.

BMC genomics - 11 Apr 2026

Ninoyu Yuzuru, Pan Calvin, Luu Jennifer, Rashid Sameeha, Johnston Jadyn, Ortega Briana, Boussaty Ely, Lu Lu, Clifford Royce, Mohammadi Pejman, Telese Francesca, Palmer Abraham A, Lusis Aldons J, Friedman Rick A

Abstract excerpt

Disequilibrium is a highly prevalent age-related condition that increases fall risk, yet the genetic architecture underlying vestibular function remains poorly defined. Here, we performed genome-wide association studies (GWAS) of vestibular-evoked potentials (VsEP) and raised-beam performance across young and aged Hybrid Mouse Diversity Panel (HMDP) strains. In young mice, we identified genome-wide significant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 41965519
DOI: 10.1186/s12864-026-12810-y
PMCID: PMC13182000

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