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Article

Drug efficacy at G protein-coupled receptors.

Annual review of pharmacology and toxicology - 1 Jan 2002

Kenakin Terry

Abstract excerpt

Efficacy has been defined in receptor pharmacology as a proportionality factor denoting the amount of physiological response a given ligand imparts to a biological system for a given amount of receptor occupancy. While first defined in terms of response, the concept can be expanded to a wide variety of G protein-coupled receptor (GPCR) behaviors, which includes pleiotropic interaction with multiple G proteins,...

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Identifiers

PMID: 11807176
DOI: 10.1146/annurev.pharmtox.42.091401.113012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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