Article
Association between the polymorphic GRM3 gene and negative symptom improvement during olanzapine treatment.
Schizophrenia research - 15 Sept 2005
Bishop Jeffrey R, Ellingrod Vicki L, Moline Jessica, Miller Del
Abstract excerpt
PURPOSE: The excitatory neurotransmitter glutamate has become an important area of focus for schizophrenia researchers. Polymorphisms in the type-three metabotropic glutamate receptor gene (GRM3) have been associated with the pathogenesis of schizophrenia. The purpose of this study was to determine whether a pharmacogenetic relationship exists between six polymorphisms of GRM3 and clinical improvement during...
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